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Naltrexone Pellet Therapy For Alcohol Addiction - FAQ


 

 WHAT IS NALTREXONE/REVIA?

Naltrexone is a prescription drug that reduces the desire to drink alcohol and improves the success rate for addiction recovery. In 1984, Revia, an oral pill form of this drug, was approved by the FDA for the treatment of opiate pain drugs (hydrocodone, oxycodone, Percocet, oxycontin, etc) and heroin addiction. After clinical experience showed naltrexone also decreased the cravings for alcohol, it was also approved for alcohol use disorder in 1994.

Studies and clinical experience show that naltrexone totally blocks the euphoric effects of heroin and opiate pain drugs and also takes away the cravings to use opiates as well. When naltrexone is given to patients with alcohol use disorder it does not block the effects of alcohol, however it does significantly decrease the desire to drink and is therefore very effective for reducing cravings and preventing relapse for those in recovery.

In the initial treatment protocol for alcohol use disorder, an oral dose of Revia was given daily and the patient was instructed to totally abstain from consuming any alcohol. Revia used in this manner was not an overwhelming clinical success mostly due to poor compliance of daily dosing. Oral dosing using Revia soon fell out of favor in most alcohol addiction recovery centers.

Recently, naltrexone was made available in a monthly injection as a prescription drug called Vivitrol®. The monthly injection eliminates the compliance problem of daily dosing, and studies found it significantly decreased the number of binge drinking days during the 30 days following the injection. This is a better option than the oral dose, but the expense for most patients and the short duration of activity also make it less than ideal as a treatment option.

Another option for delivering naltrexone is an extended release pellet placed under the skin. This option offers the best combination of a three to six-month duration of benefits with a lower cost per month for the recovering addict. While naltrexone is being slowly released into the body, the sustained level of medication continues to reduce the cravings for alcohol.

The naltrexone pellets are produced in an independent compounding pharmacy under the strictest purity, sterility and potency standards. The pellets have not undergone an FDA approval process, but they are manufactured using USP raw materials

 

ARE NALTREXONE PELLETS SAFE?

Naltrexone in all forms is relatively safe. Naltrexone pellet implants have been extremely well tolerated in the hundreds of patients treated in our office. Patients receiving the pellets obviously can expect slight bruising and discomfort for a short time after the simple procedure. There is also a very small risk of post procedure infection but this has not occurred in any of our patients.

If naltrexone therapy is performed before a patient using opiates or heroin has detoxed from those drugs, the pellet will cause immediate and severe opioid withdrawal symptoms. Also, if a patient on naltrexone therapy is in an accident where narcotic medicines are normally used for pain relief, the narcotics would have no effect.

Should the patient be injured after the procedure and require analgesia (pain medications), they must inform the doctor that they are on naltrexone maintenance therapy so an alternative medication may be prescribed. Because the patient may be involved in an accident or some other occurrence that renders him unable to inform the doctor that he is on the medication, it is recommended that they wear a bracelet our office will supply which advises the doctor that the patient is receiving naltrexone maintenance therapy.

Numerous recent studies show that a combination of oral ibuprofen alternated with acetominophen was just as effective as all opioid class prescription pain drugs for post dental, injury and surgeries.

If patients try to override the blocking effects of naltrexone and abuse narcotics they have run a dangerous risk of an overdose. Patients recovering from opiate addiction also need to be especially careful after the implant wears off because they no longer have a tolerance for the drug. The same amount of opiate drug previously used after a period of abstinence can be fatal.

 

IS NALTREXONE PELLET THERAPY A CURE TO OPIOID OR HEROIN ADDICTION? 

In a word: no. We believe strongly that naltrexone pellet therapy by itself is not a cure, but during the period of its opioid blocking effects it virtually eliminates the possibility of relapse. This is the key for many addicts that want to recover but believe it is impossible when they are dealing with the daily cravings. Freedom from the cravings, and knowing there is no reward of getting high, allows the recovering addict who is 100% committed to recovery to put all of their mental focus on a 12-step program and/or professional therapy.

Studies have shown that the best indicator of long-term recovery is continued participation in a 12-step recovery program. Most addicts have not developed the life skills and behaviors required for lifelong sobriety. This is the real work in addiction recovery and one that cannot be ignored or assumed to take care of itself while enjoying the freedom from cravings. Naltrexone therapy without the appropriate therapy and 12-step support is almost always unsuccessful.

 
HOW LONG SHOULD I STAY ON NALTREXONE THERAPY? 

We believe strongly that patients should be on naltrexone pellet therapy for a minimum of 12 months. This essentially prevents them from relapsing back to narcotic use and gives them at least a year to start making changes in their lives and working in a support group. After the first 12 months, patients should consult with Dr. Nelson and their counselor and honestly "self assess" their readiness for sobriety without naltrexone. Patients that decide they want to continue with the naltrexone therapy can receive additional pellets or transition to daily oral naltrexone medication. 

There are no long-term complications or side effects from the low dose naltrexone therapy. In fact, low dose naltrexone therapy has been found to actually strengthen and improve the immune system, and has been used successfully in illnesses such as cancer, arthritis, chronic fatigue, fibromyalgia, and MS.


AM I A CANDIDATE FOR NALTREXONE PELLET THERAPY?

Naltrexone would be appropriate for any opiate addict who desperately wants to stop using opiates but has never managed to stay sober for a long period. The term we use to best describe this person is that they are in a “state of readiness." A person may say they are ready to recover, however this will only be confirmed through their actions that will be obvious to their 12-step group, their therapist, their family and friends, etc. The recovering addict will consistently make life-affirming changes that demonstrate self-reliance and emotional maturity.

Naltrexone is very helpful for those that are ready but know that relying on will power or counseling alone will not work for them. Naltrexone is not a mood-altering drug and is therefore not objectionable to most recovery programs or sober living homes that require abstinence. Participation in a 12-step recovery program is the single most important form of follow-up care. We believe there is no substitute for the therapeutic value of one addict helping another to sobriety.

 

WHAT'S THE PROCESS OF EVALUATION AND TREATMENT WITH NALTREXONE PELLET THERAPY? 

A person needs to be free from opiates or heroin for a minimum of one week before receiving a naltrexone pellet. Those on Methadone, Suboxone® or Subutex® should be off their prescription for at least 10-14 days because these drugs take longer to clear from the body. Even if no opioids have been taken for the recommended time, there may be some mild to moderate withdrawals due to the chronic imbalance in the essential brain neurotransmitters.

We require a simple blood test, a basic screening and exam to decrease the risks and increase the success of naltrexone therapy. We will also perform a urine drug screen immediately prior to the pellet insertion.

The procedure is simple and takes just a few minutes to perform. The doctor will numb the area and then make a small incision and place one pellet (3 month duration) or two pellets (6 month) under the skin. The incision is closed with a few stitches and the patient is sent home or could even go back to work if they desire.

It is recommended that patients wear a Medic-Alert tag (bracelet or necklace) that would inform a treating physician that the patient is on naltrexone maintenance therapy in the event that the patient is not able to communicate this information. The physician would obviously need to prescribe a non-opiate medication if pain relief was required. 

There are very few side effects from naltrexone and none of them are serious. It is difficult to determine whether the symptoms that are sometimes experienced are due to the naltrexone or the last remnants of the withdrawal syndrome. The withdrawal symptoms do not occur with every patient, especially if the addict has not used drugs for an extended period. Even if the patient experiences some withdrawal symptoms, they are generally mild compared to acute withdrawals experienced during drug detox, and cease within a week or so.

 

ARE FOLLOW UP APPOINTMENTS NECESSARY?

Approximately one week after the procedure, patients may return to the clinic to have the stitches removed. On an ongoing basis, it is important to receive the next pellet before the effects wear off to prevent relapse. Patients are advised to schedule their next pellet insertions three or six months out at this time. If a patient is still free from cravings at the three or six month time frame, we recommend a blood test to accurately determine the serum level of the naltrexone to ensure it is at the ideal therapeutic level. Although our single pellet lasts around 3 months and two pellets last approximately 6 months, the duration of effectiveness varies with each individual.  

 

HOW DO I DETERMINE WHEN TO SCHEDULE THE NEXT PELLET INSERTION?

Approximately one week after the procedure, patients may return to the clinic to have the stitches removed. On an ongoing basis, it is important to receive the next pellet before the effects wear off to prevent relapse. Patients are advised to schedule their next pellet insertions three or six months out at this time. If a patient is still free from cravings at the three or six month time frame, we recommend a blood test to accurately determine the serum level of the naltrexone to ensure it is at the ideal therapeutic level. Although our single pellet lasts around 3 months and two pellets last approximately 6 months, the duration of effectiveness varies with each individual.  


HOW MUCH DOES THE PROCEDURE COST?

The cost of the initial consultation is $295. This includes a full review of the patient history and an intake screening exam. All patients are required to provide recent (within 60 days) blood work consisting of a CBC with metabolic panel and a urinalysis. If it is determined the patient is a good candidate for Naltrexone therapy, a pellet order will be placed with our compounding pharmacy at this time. Usually, we can schedule the pellet procedure for one week after the initial exam. Many patients have found it is best to coordinate their schedule so they can have their pellet procedure performed immediately after they complete their inpatient detoxification program. 

FEE SCHEDULE
Initial intake and exam                  $295
Urine Drug screen                          $40
Two pellet insertion                        $1695


About Dr. Nelson

Dr. William Nelson has over 20 years of experience integrating the latest advances in medical science with time-honored therapies of Naturopathic medicine. He is an expert in naltrexone therapy for opiate, heroin, and alcohol addiction recovery, prolotherapy for non-surgical knee, shoulder, hip repair and back pain, fatigue due to thyroid and adrenal disorders, bio-identical hormone pellet therapy for men and women, and nutritional therapy to help rebuild the damaged neurotransmitter system after years of substance abuse. Doctor Nelson hosts a weekly podcast on addiction recovery that averages over 6000 monthly downloads.

"Over the last five years, I became extremely frustrated and saddened because I couldn't help a loved one that desperately needed help to overcome her addiction. Because of the benefits of Naltrexone pellet therapy, she is now sober and on the road to recovery. This life-saving therapy is ideal for those who desperately want to become drug and/or alcohol free, but have experienced failures in trying to do so that make that goal seem next to impossible. My personal mission is to help other patients and their families the same way I was able to help my family member."

For more information: Dr. Nelson’s podcast https://starworldwidenetworks.com/shows/your-road-to-personal-addiction-recovery

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Explore Health
7320 E Deer Valley, Ste 100
North Scottsdale, AZ 85255
Phone: 602-562-4214
Fax: 480-418-3637
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