
What are the best alternatives to cortisone shots and surgery for joint, low back and neck pain?

What is Regenerative Orthopedics, Prolotherapy and PRP?
Regenerative orthopedics includes various forms of regenerative injections which are safe and effective treatments for acute and chronic pain in joints and the spine. Regenerative injections are non-surgical in-office procedures that require no downtime for recovery. Since 1996, Dr. William Nelson, of Scottsdale, AZ, has helped thousands of people become pain free, allowing them to avoid surgery, opiate pain relievers, and harmful cortisone shots (which damages soft tissue and cartilage).
What conditions can be treated with regenerative injections?
Our office treats all chronic and acute musculoskeletal and nerve pain. The most common conditions we have treated are knee, low back, shoulder and hip pain. In addition, Dr. Nelson is an expert in treating the following conditions:
- Low back pain – ligament, tendon, and facet capsule injuries, mild degenerative discs
- Whiplash, Post concussion, ligament and tendon sprains
- Shoulder – torn rotator cuff, full and partial thickness tendon tears, tendonitis, frequent dislocations, bursitis, labral tears, nerve pain, osteoarthritis, and frozen shoulder
- Hip – Osteoarthritis, ligament and tendon injury, bursitis, torn labrum
- Knee – MCL, LCL, ACl, PCL tears, osteoarthritis, baker’s cysts, torn meniscus
- Ankle/foot – high ankle sprain, tarsal tunnel syndrome, plantar’s fasciitis,
- Elbow – golfer’s and tennis elbow
- Hand/wrist – carpal tunnel syndrome,
- Nerves – chronic constriction injuries, peripheral nerve inpingment.
- Temporal mandibular (TMJ) pain and dysfunction
What is the success rate for Regenerative injections?
According to a American Osteopathic Association of Medicine study , approximately 80% of patients receiving proltherapy received at least a 50% decrease in pain. The anticipated rate of success depends on a number of variables, including the patient’s history and ability to heal, and the type of solution used. In patients with low back pain, studies have shown 85% to 95% of patients experience improvement with prolotherapy (compared to studies showing only a 52% improvement with back surgery).
In our clinical experience with thousands of patients over the last 30 years, we estimate we have a 80-90% success rate. Depending on the severity of structural injury, the age and health status of the patient, resolution of pain and dysfunction can require anywhere from one to five+ treatments spread out over 6 months to one year.
What are the various types of regenerative injections?
- Standard Dextrose Prolotherapy – This therapy has been safely and effective utilized for joint and spine regeneration since the 1950’s. The injections utilize off the shelf sterile products including 50% dextrose, normal saline, local anesthesia (lidocaine or ropivacaine), and ketorolac (an analgesic). The net effect of the injection is to cause a mild injury in the compromised soft tissue by injecting a solution which is a mild tissue irritant. This initiates an inflammatory response that predictably results in a strengthening and healing of the soft tissue injury.
- PRP with or without A2M – Platelet Rich Plasma and A2M are biological injections that are derived from the patient’s blood. A simple blood draw followed by a concentration procedure produces the PRP/A2M that has a similar but stronger regenerative effect when compared with Standard Dextrose Prolotherapy. PRP is utilized for patients with more severe soft tissue injuries such as partially torn or full thickness ligament or tendon tears. A2M is utilized for patients with cartilage degeneration. For soft tissue injuries, one PRP treatment is equivalent to approximately 3 Standard Prolotherapy injections.
- Wharton’s Jelly – Wharton’s Jelly is a biological product that is extracted and processed from the umbilical cord after a healthy birth. The product is considered a connective tissue supplementation that provides the biological building blocks and matrix to fill the voids and defects in the patient’s weight bearing surfaces (cartilage) and soft tissue (ligaments, tendons, and joint capsule) stabilizing and holding the joints in proper position. This product provides naturally occurring hyaluronic acid, growth factors, peptides, and stem cell derived extra-cellular vesicles for the most effective therapy for repairing osteoarthritis and severe soft tissue injuries.
How do prolotherapy and PRP injections work?
All three of the above treatments work in a similar manner. They help by initiating a biological healing response that strengthens the connective tissue to improve the structural alignment of the injured joint to decrease pain, improve the joint’s range of motion and reduce the abhorrent movement which increases the rate of joint degeneration.
Are prolotherapy and PRP injections similar to cortisone shots?
These treatments dramtically different from cortisone/steroid injections. Cortisone provides temporary relief by shutting down joint inflammation and pain. The injections do nothing to heal the compromised tissue and actually damage the ligaments, tendons, and cartilage. We compare this to taking the batteries out of your smoke alarm when it is beeping.
In contrast, accurately placed regenerative injections initiate the body’s self-healing mechanism to regenerate and restore injured tissues. This reduces the pain and stiffness while restoring the strength and function of the joint.
What is regional hyperthermia? Can hyperthermia help improve the results of my prolotherapy or PRP injections?
Recently, our office has added a post-procedure therapy called regional hyperthermia to augment our regenerative injection therapies. Regional hyperthermia is a safe, simple, and pain free application of heat to the injured area to increase the internal temperature of the tissue up to 112 degrees F. Our German made medical device is one of a kind and safely heats the target tissue to depths of up to 5 inches while preventing burning the skin by utilizing computer-controlled temperature sensors. Hyperthermic heating of the target tissue increases blood flow 1500% to increase the delivery of oxygen, nutrients, and natural biological substances (platelets, growth factors, cytokines, peptides, fibroblasts, stem cells, etc) to optimize the results of your injection procedure.
Does your office offer a free consult?
Although many other providers offer a free consult, our office has reduced the fee for our $295 inital consult to $99. The consult includes a thorough review of your diagnostic imaging (MRI, Xray, Ultrasound, etc), an orthopedic and neurological exam, and an in-house ultrasound exam of the soft tissue.
Can supplements, hormones and peptides improve my results of PRP and prolotherapy?
Optimal clinical outcomes are achieved by making sure your body has the essential nutrients and building blocks to rebuild and regenerate your damaged tissues. Ask about our total regeneration program that includes a comprehensive blood test (including screening for inflammation, nutrient deficiencies, metabolic dysfunction and hormone deficiencies). In addition, this program includes screening for common underlying causes for pain including chronic infection(s), metal toxicity, unresolved dental problems, chronic nerve constrictions, negative influences of surgical or traumatic scars, etc. The results of your regenerative injections will be optimized after implementing your individualized regenerative program.
Testimonial. "When one of Phoenix's "Top Docs" couldn't help"
"I was severely injured and my car totaled in a motor vehicle accident. After the accident, I was suffering from excrutiating neck, mid, and low back pain. I received physical therapy (15 sessions) and multiple treatments from a renouned "Phoenix Top Doc" spine and sports specialist (several epidurals and medial branch blocks). These treatments gave me no relief. I was referred to an orthopedic surgeon and was devastated when I was told there was nothing else they could do to help me out of my acute pain. Luckily, I found my way to Dr. Nelson's office. After 5 prolotherapy sessions over six months, I was pain free. I am so grateful to Stephanie and Dr. Nelson for giving me my life back." M. T.
How can I choose the best provider for prolotherapy, PRP and regenerative injections?
Thank you for your interest in our practice. Since 1996, Dr. Nelson has been providing successful clinical outcomes for thousands of patients. Many of his successful patients were given relief after failing to respond to regenerative injections from other stem cell clinics, PRP providers, or "Phoenix Top Docs"You Might Also Enjoy...


What are treatment options for Plantar Faciitis?

Is your hip replacement surgery medically necessary? How can you obtain a second opinion.

Non-surgical knee specialist recommends the best treatment to avoid knee replacement?

Telehealth: The Advantages of Telemedicine
